Neuroscience:Translate

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The Neuroscience:Translate grant program supports research projects at the intersection of biology, engineering and medicine to address practical unmet needs in brain health and the neurosciences.

The program funds cross-disciplinary teams to develop new devices, diagnostic procedures, software, pharmaceutical therapies and other products that can be brought rapidly to market through new startup companies or partnerships with existing companies. Grants of up to $100,000 are awarded annually to approximately six teams. Teams who have previously received Neuroscience:Translate awards may apply for a one-year renewal to continue advancing their technology.


This program was inspired by the successful Stanford Coulter Translational Research program, a partnership between Stanford Bioengineering and the Coulter Foundation managed by the Stanford Byers Center for Biodesign. The Wu Tsai Neurosciences Institute partners with Stanford Biodesign to bring this approach and expertise to bear on the field of neuroscience and brain diseases, with guidance from a Neuroscience:Translate oversight committee comprising scientific and industry leaders in biotechnology development.

Closed

2024 applications are closed

Funded Neuroscience:Translate projects

Wu Tsai Neurosciences Institute
Neuroscience:Translate Award
2020
Targeting DNA repair for neuroinflammation in stroke
Acute brain inflammation after stroke and head trauma causes adverse health outcomes affecting millions of patients each year in the U.S., and current treatments are insufficient. This project will test a promising new therapy to reduce inflammation by targeting the enzyme OGG1, a potentially important controller of acute inflammatory responses. This project is jointly supported by the Wu Tsai Neurosciences Institute and SPARK.
Wu Tsai Neurosciences Institute
Neuroscience:Translate Award
2022
Remote reliable measurements of movement using bluetooth enabled engineered keyboard for diagnosis of neurological diseases - Renewal

This team is developing a device that will enable accurate diagnosis of Parkinson’s disease via telemedicine. They initially introduced the technology of Quantitative DigitoGraphy (QDG) using a repetitive alternating finger tapping (RAFT) task on a musical instrument digital interface (MIDI) keyboard and will use Neuroscience: Translate funding for the next stage of device development.

Wu Tsai Neurosciences Institute
Neuroscience:Translate Award
2021
The wearable ENG: a dizzy attack event monitor, Dizzy DX - Renewal
Recurrent dizziness attacks are a debilitating condition for 10% of the population during their lifetime, and can lead to a complete inability to function, and to multiple hospital admissions and investigations chasing many potential diagnoses. This project aims to address the unmet need for means of tracking patients' specific symptoms, so that correct treatments can be identified that will improve patients' function and quality of life.
Wu Tsai Neurosciences Institute
Neuroscience:Translate Award
2021
A minimally-invasive intracranial pressure microsensor (mICP) for long-term, continuous ambulatory monitoring
The limited available treatments (e.g., radiation, chemotherapy) for glioblastoma (GBM) can lead to swelling in the brain that causes elevated intracranial pressure (ICP), the timing of which is unpredictable; this results in the patient presenting to the emergency room with headaches, vomiting, or seizures, which leads to worsened quality of life and survival outcomes. We propose the refinement and pre-clinical validation of a pressure-sensing microfluidic ICP microsensor (mICP) that could be implanted in patients with GBM to detect elevated ICP early on.
Wu Tsai Neurosciences Institute
Neuroscience:Translate Award
2022
Development of an extracochlear neurostimulation device to restore hearing – Renewal

Sensorineural hearing loss is an increasingly prevalent condition that causes disability to over a third of US adults aged over 65. This team is developing a breakthrough device to restore high-frequency hearing that preserves residual hearing through a reversible and minimally invasive approach.

Wu Tsai Neurosciences Institute
Neuroscience:Translate Award
2023
New Thrombectomy Device for Endovascular Neurosurgery

This team will use their Neuroscience:Translate award to develop an entirely new class of ischemic stroke treatment device that will lead to improved clot extraction to improve the success of endovascular thrombectomy.